Computational Modeling

Residual-Based Error Correction for Neural Operator Accelerated Infinite-Dimensional Bayesian Inverse Problems

We explore using neural operators, or neural network representations of nonlinear maps between function spaces, to accelerate infinite-dimensional Bayesian inverse problems (BIPs) with models governed by nonlinear parametric partial differential …

Mutual-Information Based Optimal Experimental Design for Hyperpolarized 13C-Pyruvate MRI

A key parameter of interest recovered from hyperpolarized (HP) MRI measurements is the apparent pyruvate-to-lactate exchange rate, kPL, for measuring tumor metabolism. This manuscript presents an information-theory-based optimal experimental design …

Bayesian-Based Predictions of COVID-19 Evolution in Texas Using Multispecies Mixture-Theoretic Continuum Models

We consider a mixture-theoretic continuum model of the spread of COVID-19 in Texas. The model consists of multiple coupled partial differential reaction–diffusion equations governing the evolution of susceptible, exposed, infectious, recovered, and …